|
MEK162系列产品详情及市场趋势MEK162 is a potent and selective mitogen–activated protein kinase (MEK) inhibitor wirh IC50 of 12 nM. IC50 & Target: IC50: 12 nM (MEK)[1] n Vitro: In MCF7 cells, RSK3 or RSK4 expression decreases response to treatment with any of the PI3K inhibitors alone. However, the combination of PI3K inhibition with MEK162 or BI-D1870 completely reverses the resistance of RSK-expresing.
|
